A dendritic cell-targeted chimeric hepatitis B virus immunotherapeutic vaccine induces both cellular and humoral immune responses in vivo

A dendritic cell-targeted chimeric hepatitis B virus immunotherapeutic vaccine induces both cellular and humoral immune responses in vivo

Chimigen® HBV Immunotherapeutic Vaccine (C-HBV), a recombinant chimeric fusion protein comprising hepatitis B virus (HBV) S1 and S2 surface antigen fragments, Core antigen and a murine monoclonal antibody heavy chain fragment (Fc), was designed and produced in Sf9 insect cells. C-HBV targets the hos...

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Bibliographic Details
Main Authors: Rajan George, Allan Ma, Bruce Motyka, Yuenian Eric Shi, Qiang Liu, Philip Griebel
Format: Article
Language:English
Published: Taylor & Francis Group 2020-04-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
immunotherapy
vaccine
hepatitis b virus
dendritic cells
immune responses
fusion protein
Online Access:http://dx.doi.org/10.1080/21645515.2019.1689081

Internet

http://dx.doi.org/10.1080/21645515.2019.1689081

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