Role of GRK6 in the Regulation of Platelet Activation through Selective G Protein-Coupled Receptor (GPCR) Desensitization

Role of GRK6 in the Regulation of Platelet Activation through Selective G Protein-Coupled Receptor (GPCR) Desensitization

Platelet G protein-coupled receptors (GPCRs) regulate platelet function by mediating the response to various agonists, including adenosine diphosphate (ADP), thromboxane A<sub>2</sub>, and thrombin. Although GPCR kinases (GRKs) are considered to have the crucial roles in most GPCR functi...

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Bibliographic Details
Main Authors: Preeti Kumari Chaudhary, Sanggu Kim, Youngheun Jee, Seung-Hun Lee, Kyung-Mee Park, Soochong Kim
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
GRK6
GPCR
PAR
ADP
desensitization
platelets
Online Access:https://www.mdpi.com/1422-0067/21/11/3932

Internet

https://www.mdpi.com/1422-0067/21/11/3932

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