Expression of calcium pumps is differentially regulated by histone deacetylase inhibitors and estrogen receptor alpha in breast cancer cells

Expression of calcium pumps is differentially regulated by histone deacetylase inhibitors and estrogen receptor alpha in breast cancer cells

Abstract Background Remodeling of Ca2+ signaling is an important step in cancer progression, and altered expression of members of the Ca2+ signaling toolkit including the plasma membrane Ca2+ ATPases (PMCA proteins encoded by ATP2B genes) is common in tumors. Methods In this study PMCAs were examine...

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Bibliographic Details
Main Authors: Karolina Varga, Anna Hollósi, Katalin Pászty, Luca Hegedűs, Gergely Szakács, József Tímár, Béla Papp, Ágnes Enyedi, Rita Padányi
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Cancer
Subjects:
PMCA
Ca2+ signaling
Breast cancer cell lines
ER-α
17β-estradiol
HDAC inhibitors
Online Access:http://link.springer.com/article/10.1186/s12885-018-4945-x

Internet

http://link.springer.com/article/10.1186/s12885-018-4945-x

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