Transcriptomic analyses of gastrulation-stage mouse embryos with differential susceptibility to alcohol

Transcriptomic analyses of gastrulation-stage mouse embryos with differential susceptibility to alcohol

Genetics are a known contributor to differences in alcohol sensitivity in humans with fetal alcohol spectrum disorders (FASDs) and in animal models. Our study profiled gene expression in gastrulation-stage embryos from two commonly used, genetically similar mouse substrains, C57BL/6J (6J) and C57BL/...

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Bibliographic Details
Main Authors: Karen E. Boschen, Travis S. Ptacek, Matthew E. Berginski, Jeremy M. Simon, Scott E. Parnell
Format: Article
Language:English
Published: The Company of Biologists 2021-06-01
Series:Disease Models & Mechanisms
Subjects:
fetal alcohol spectrum disorders
apoptosis
inflammation
embryo
brain development
Online Access:http://dmm.biologists.org/content/14/6/dmm049012

Internet

http://dmm.biologists.org/content/14/6/dmm049012

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