Human bronchial carcinoid tumor initiating cells are targeted by the combination of acetazolamide and sulforaphane

Human bronchial carcinoid tumor initiating cells are targeted by the combination of acetazolamide and sulforaphane

Abstract Background Bronchial carcinoids are neuroendocrine tumors that present as typical (TC) and atypical (AC) variants, the latter being more aggressive, invasive and metastatic. Studies of tumor initiating cell (TIC) biology in bronchial carcinoids has been hindered by the lack of appropriate i...

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Bibliographic Details
Main Authors: Reza Bayat Mokhtari, Narges Baluch, Evgeniya Morgatskaya, Sushil Kumar, Angelo Sparaneo, Lucia Anna Muscarella, Sheyun Zhao, Hai-Ling Cheng, Bikul Das, Herman Yeger
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Cancer
Subjects:
Bronchial carcinoid
Acetazolamide
Sulforaphane
Orthotopic lung model
Combination therapy
3D spheroids
Online Access:http://link.springer.com/article/10.1186/s12885-019-6018-1

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http://link.springer.com/article/10.1186/s12885-019-6018-1

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