Sex-Specific Cell Types and Molecular Pathways Indicate Fibro-Calcific Aortic Valve Stenosis

Sex-Specific Cell Types and Molecular Pathways Indicate Fibro-Calcific Aortic Valve Stenosis

BackgroundAortic stenosis (AS) is the most common valve disorder characterized by fibro-calcific remodeling of leaflets. Recent evidence indicated that there is a sex-related difference in AS development and progression. Fibrotic remodeling is peculiar in women’s aortic valves, while men’s leaflets...

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Bibliographic Details
Main Authors: Veronika A. Myasoedova, Ilaria Massaiu, Donato Moschetta, Mattia Chiesa, Paola Songia, Vincenza Valerio, Valentina Alfieri, Romain Capoulade, Daniela Trabattoni, Daniele Andreini, Elvira Mass, Valentina Parisi, Paolo Poggio
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
Subjects:
aortic valve stenoses
fibrosis
inflammation
immune system
sex-difference
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.747714/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.747714/full

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