The NF-κB Pathway and Cancer Stem Cells

The NF-κB transcription factor pathway is a crucial regulator of inflammation and immune responses. Additionally, aberrant NF-κB signaling has been identified in many types of cancer. Downstream of key oncogenic pathways, such as RAS, BCR-ABL, and Her2, NF-κB regulates transcription of target genes...

Full description

Bibliographic Details
Main Authors: Amanda L. Rinkenbaugh, Albert S. Baldwin
Format: Article
Language:English
Published: MDPI AG 2016-04-01
Series:Cells
Subjects:
Online Access:http://www.mdpi.com/2073-4409/5/2/16