The NF-κB Pathway and Cancer Stem Cells
The NF-κB transcription factor pathway is a crucial regulator of inflammation and immune responses. Additionally, aberrant NF-κB signaling has been identified in many types of cancer. Downstream of key oncogenic pathways, such as RAS, BCR-ABL, and Her2, NF-κB regulates transcription of target genes...
Main Authors: | Amanda L. Rinkenbaugh, Albert S. Baldwin |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-04-01
|
Series: | Cells |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4409/5/2/16 |
Similar Items
-
The Transcription Factor NF-κB in Stem Cells and Development
by: Christian Kaltschmidt, et al.
Published: (2021-08-01) -
Targeting NF-κB Signaling in Cancer Stem Cells: A Narrative Review
by: Barbara Kaltschmidt, et al.
Published: (2022-01-01) -
CARMA3 Promotes Colorectal Cancer Cell Motility and Cancer Stemness via YAP-Mediated NF-κB Activation
by: Ting-Yu Chang, et al.
Published: (2021-11-01) -
The Stemness-High Human Colorectal Cancer Cells Promote Angiogenesis by Producing Higher Amounts of Angiogenic Cytokines via Activation of the Egfr/Akt/Nf-κB Pathway
by: Shin-Yi Chung, et al.
Published: (2021-01-01) -
Disruption of the NF-κB/IL-8 Signaling Axis by Sulconazole Inhibits Human Breast Cancer Stem Cell Formation
by: Hack Sun Choi, et al.
Published: (2019-08-01)