Cooperative function of oncogenic MAPK signaling and the loss of Pten for melanoma migration through the formation of lamellipodia

Cooperative function of oncogenic MAPK signaling and the loss of Pten for melanoma migration through the formation of lamellipodia

Abstract The combination of oncogenes and tumor suppressors is involved in cancer development; however, it is still unknown whether their combination plays a critical role in cancer metastasis. We herein investigated whether genetic combinations affected cell migration ability by establishing the im...

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Bibliographic Details
Main Authors: Yutaka Yasuta, Ryuya Kaminaka, Shutaro Nagai, Shuto Mouri, Katsuya Ishida, Akihiro Tanaka, Yue Zhou, Hiroaki Sakurai, Satoru Yokoyama
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-52020-8

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https://doi.org/10.1038/s41598-024-52020-8

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