Chronic kidney disease alters lipid trafficking and inflammatory responses in macrophages: effects of liver X receptor agonism

Chronic kidney disease alters lipid trafficking and inflammatory responses in macrophages: effects of liver X receptor agonism

Abstract Background Our aim was to evaluate lipid trafficking and inflammatory response of macrophages exposed to lipoproteins from subjects with moderate to severe chronic kidney disease (CKD), and to investigate the potential benefits of activating cellular cholesterol transporters via liver X rec...

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Bibliographic Details
Main Authors: Ryohei Kaseda, Yohei Tsuchida, Hai-Chun Yang, Patricia G. Yancey, Jianyong Zhong, Huan Tao, Aihua Bian, Agnes B. Fogo, Mac Rae F. Linton, Sergio Fazio, Talat Alp Ikizler, Valentina Kon
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Nephrology
Subjects:
HDL
CKD
Macrophages
Cholesterol efflux
LXR
Online Access:http://link.springer.com/article/10.1186/s12882-018-0814-8

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http://link.springer.com/article/10.1186/s12882-018-0814-8

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