Broad Serotonergic Actions of Vortioxetine as a Promising Avenue for the Treatment of L-DOPA-Induced Dyskinesia

Broad Serotonergic Actions of Vortioxetine as a Promising Avenue for the Treatment of L-DOPA-Induced Dyskinesia

Parkinson’s Disease (PD) is a neurodegenerative disorder characterized by motor symptoms that result from loss of nigrostriatal dopamine (DA) cells. While L-DOPA provides symptom alleviation, its chronic use often results in the development of L-DOPA-induced dyskinesia (LID). Evidence suggests that...

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Bibliographic Details
Main Authors: Carla Budrow, Kayla Elder, Michael Coyle, Ashley Centner, Natalie Lipari, Sophie Cohen, John Glinski, N’Senga Kinzonzi, Emily Wheelis, Grace McManus, Fredric Manfredsson, Christopher Bishop
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cells
Subjects:
levodopa-induced dyskinesia
Parkinson’s disease
serotonin
dopamine
serotonin transporter
5-HT<sub>1A</sub> receptor
Online Access:https://www.mdpi.com/2073-4409/12/6/837

Internet

https://www.mdpi.com/2073-4409/12/6/837

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