An engineered transcription factor which activates VEGF-A enhances recovery after spinal cord injury

An engineered transcription factor which activates VEGF-A enhances recovery after spinal cord injury

Spinal cord injury (SCI) leads to local vascular disruption and progressive ischemia, which contribute to secondary degeneration. Enhancing angiogenesis through the induction of vascular endothelial growth factor (VEGF)-A expression therefore constitutes an attractive therapeutic approach. Moreover,...

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Bibliographic Details
Main Authors: Yang Liu, Sarah Figley, S. Kaye Spratt, Gary Lee, Dale Ando, Richard Surosky, Michael G. Fehlings
Format: Article
Language:English
Published: Elsevier 2010-02-01
Series:Neurobiology of Disease
Subjects:
SCI
ZFP-VEGF
Angiogenesis
Neuroprotection
Molecular therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109003040

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http://www.sciencedirect.com/science/article/pii/S0969996109003040

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