MSC-derived exosomes attenuate cell death through suppressing AIF nucleus translocation and enhance cutaneous wound healing

MSC-derived exosomes attenuate cell death through suppressing AIF nucleus translocation and enhance cutaneous wound healing

Abstract Background Skin wounding is very common and may be slow to heal. Increasing evidence shows that exosomes derived from mesenchymal stem cells (MSCs) dramatically enhance skin wound healing in a paracrine manner. However, the mechanism underlying this phenomenon has not yet been elucidated. T...

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Bibliographic Details
Main Authors: Guifang Zhao, Feilin Liu, Zinan Liu, Kuiyang Zuo, Bo Wang, Yuying Zhang, Xing Han, Aobo Lian, Yuan Wang, Mingsheng Liu, Fei Zou, Pengdong Li, Xiaomei Liu, Minghua Jin, Jin Yu Liu
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Stem Cell Research & Therapy
Subjects:
Apoptosis
Apoptosis-inducing factor
Exosomes
Mesenchymal stem cells
Poly (ADP-ribose) polymerase-1
Protease-activated receptor
Online Access:http://link.springer.com/article/10.1186/s13287-020-01616-8

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http://link.springer.com/article/10.1186/s13287-020-01616-8

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