Structural and kinetic insights into flavin-containing monooxygenase and calponin-homology domains in human MICAL3

Structural and kinetic insights into flavin-containing monooxygenase and calponin-homology domains in human MICAL3

MICAL is an oxidoreductase that participates in cytoskeleton reorganization via actin disassembly in the presence of NADPH. Although three MICALs (MICAL1, MICAL2 and MICAL3) have been identified in mammals, only the structure of mouse MICAL1 has been reported. Here, the first crystal structure of hu...

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Bibliographic Details
Main Authors: Junsoo Kim, Haemin Lee, Yeon Jin Roh, Han-ul Kim, Donghyuk Shin, Sorah Kim, Jonghyeon Son, Aro Lee, Minseo Kim, Junga Park, Seong Yun Hwang, Kyunghwan Kim, Yong Kwon Lee, Hyun Suk Jung, Kwang Yeon Hwang, Byung Cheon Lee
Format: Article
Language:English
Published: International Union of Crystallography 2020-01-01
Series:IUCrJ
Subjects:
mical
actin depolymerization
calponin-homology domain
f-actin
monooxygenases
structure determination
protein structure
refinement
x-ray crystallography
enzyme mechanisms
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2052252519015409

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http://scripts.iucr.org/cgi-bin/paper?S2052252519015409

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