High throughput clone screening on overexpressed hERG1 and Kv1.3 potassium channels using ion channel reader (ICR) label free technology

Pharmacological studies aimed at the development of newly synthesized drugs directed against ion channels (as well as genetic studies of ion channel mutations) involve the development and use of transfected cells. However, the identification of the best clone, in terms of transfection efficiency, is...

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Bibliographic Details
Main Authors: Alberto Montalbano, Cesare Sala, Ginevra Chioccioli Altadonna, Andrea Becchetti, Annarosa Arcangeli
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023073206