Cytoreduction surgery reduces systemic myeloid suppressor cell populations and restores intratumoral immunotherapy effectiveness

<p>Abstract</p> <p>Background</p> <p>Multiple immunotherapy approaches have improved adaptive anti-tumor immune responses in patients with early stage disease; however, results have been less dramatic when treating patients with late stage disease. These blunted respons...

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Bibliographic Details
Main Authors: Predina Jarrod D, Kapoor Veena, Judy Brendan F, Cheng Guanjun, Fridlender Zvi, Albelda Steven M, Singhal Sunil
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:http://www.jhoonline.org/content/5/1/34