The Cytotoxic Effects of Betulin-Conjugated Gold Nanoparticles as Stable Formulations in Normal and Melanoma Cells

The Cytotoxic Effects of Betulin-Conjugated Gold Nanoparticles as Stable Formulations in Normal and Melanoma Cells

Gold nanoparticles are currently investigated as theranostics tools in cancer therapy due to their proper biocompatibility and increased efficacy related to the ease to customize the surface properties and to conjugate other molecules. Betulin, [lup-20(29)-ene-3β, 28-diol], is a pentacyclic triterpe...

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Bibliographic Details
Main Authors: Marius Mioc, Ioana Zinuca Pavel, Roxana Ghiulai, Dorina E. Coricovac, Claudia Farcaş, Ciprian-Valentin Mihali, Camelia Oprean, Vlad Serafim, Ramona A. Popovici, Cristina A. Dehelean, Michael I. Shtilman, Aristidis M. Tsatsakis, Codruţa Şoica
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Pharmacology
Subjects:
gold nanoparticles
betulin
skin
apoptosis
melanoma
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00429/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2018.00429/full

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