Lung-protective ventilation suppresses systemic and hepatic vein levels of cell-free DNA in porcine experimental post-operative sepsis

Lung-protective ventilation suppresses systemic and hepatic vein levels of cell-free DNA in porcine experimental post-operative sepsis

Abstract Background Plasma levels of cell-free DNA (cf-DNA) are known to be elevated in sepsis and high levels are associated with a poor prognosis. Mechanical ventilation affects systemic inflammation in which lung-protective ventilation attenuates the inflammatory response. The aim was to study th...

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Bibliographic Details
Main Authors: Axel Nyberg, Alexander Larsson, Juulia Jylhävä, Mikko Hurme, Jesper Sperber, Miklós Lipcsey, Markus Castegren
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Pulmonary Medicine
Subjects:
Innate immunity
Cytokines
Endotoxin
Low tidal volume ventilation
Intensive care
Online Access:http://link.springer.com/article/10.1186/s12890-020-01239-y

Internet

http://link.springer.com/article/10.1186/s12890-020-01239-y

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