The function of a spindle checkpoint gene bub-1 in C. elegans development.
BACKGROUND:The serine/threonine kinase BUB1 (Budding Uninhibited by Benzimidazole 1) was originally identified in yeast as a checkpoint protein, based on its mutant's incapacity of delaying the cell cycle in response to loss of microtubules. Our understanding of its function is primarily from s...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-06-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2691579?pdf=render |