Large scale plasma proteomics identifies novel proteins and protein networks associated with heart failure development

Large scale plasma proteomics identifies novel proteins and protein networks associated with heart failure development

Abstract Heart failure (HF) causes substantial morbidity and mortality but its pathobiology is incompletely understood. The proteome is a promising intermediate phenotype for discovery of novel mechanisms. We measured 4877 plasma proteins in 13,900 HF-free individuals across three analysis sets with...

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Bibliographic Details
Main Authors: Amil M. Shah, Peder L. Myhre, Victoria Arthur, Pranav Dorbala, Humaira Rasheed, Leo F. Buckley, Brian Claggett, Guning Liu, Jianzhong Ma, Ngoc Quynh Nguyen, Kunihiro Matsushita, Chiadi Ndumele, Adrienne Tin, Kristian Hveem, Christian Jonasson, Håvard Dalen, Eric Boerwinkle, Ron C. Hoogeveen, Christie Ballantyne, Josef Coresh, Torbjørn Omland, Bing Yu
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-44680-3

Internet

https://doi.org/10.1038/s41467-023-44680-3

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