Small interfering RNA against BCR-ABL transcripts sensitize mutated T315I cells to nilotinib
Background Selective inhibition of the BCR-ABL tyrosine kinase by RNA interference has been demonstrated in leukemic cells. We, therefore, evaluated specific BCR-ABL small interfering RNA silencing in BCR-ABL-positive cell lines, including those resistant to imatinib and particularly those with the...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Ferrata Storti Foundation
2010-03-01
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| Series: | Haematologica |
| Online Access: | https://haematologica.org/article/view/5524 |