Protection against atherosclerosis by estrogen is independent of plasma cholesterol levels in LDL receptor-deficient mice
Low density lipoprotein (LDL) receptor-deficient (LDLR–/–) mice consuming a high fat diet were used to assess the effect of endogenous and exogenous estradiol (E2) on atherosclerosis. Sexually mature female mice were ovariectomized (OVX) and implanted with subcutaneous, slow-release pellets designed...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
1999-05-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520321246 |