Insight into the underlying molecular mechanism of dilated cardiomyopathy through integrative analysis of data mining, iTRAQ-PRM proteomics and bioinformatics

Insight into the underlying molecular mechanism of dilated cardiomyopathy through integrative analysis of data mining, iTRAQ-PRM proteomics and bioinformatics

Abstract Background DCM is a common cardiomyopathy worldwide, which is characterized by ventricular dilatation and systolic dysfunction. DCM is one of the most widespread diseases contributing to sudden death and heart failure. However, our understanding of its molecular mechanisms is limited becaus...

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Bibliographic Details
Main Authors: Hongli Xiong, Zhe Zheng, Congcong Zhao, Minzhu Zhao, Qi Wang, Peng Zhang, Yongguo Li, Ying Zhu, Shisheng Zhu, Jianbo Li
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Proteome Science
Subjects:
Dilated cardiomyopathy
Molecular pathways
Gene network
Bioinformatics
Mechanisms
Online Access:https://doi.org/10.1186/s12953-023-00214-9

Internet

https://doi.org/10.1186/s12953-023-00214-9

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