Beneficial Effect of Dimethyl Fumarate Drug Repositioning in a Mouse Model of TDP-43-Dependent Frontotemporal Dementia

Beneficial Effect of Dimethyl Fumarate Drug Repositioning in a Mouse Model of TDP-43-Dependent Frontotemporal Dementia

Frontotemporal dementia (FTD) causes progressive neurodegeneration in the frontal and temporal lobes, leading to behavioral, cognitive, and language impairments. With no effective treatment available, exploring new therapeutic approaches is critical. Recent research highlights the transcription fact...

Full description

Bibliographic Details
Main Authors: Ignacio Silva-Llanes, Raquel Martín-Baquero, Alicia Berrojo-Armisen, Carmen Rodríguez-Cueto, Javier Fernández-Ruiz, Eva De Lago, Isabel Lastres-Becker
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Antioxidants
Subjects:
NRF2
TDP-43
DMF
neurodegeneration
neuroinflammation
Online Access:https://www.mdpi.com/2076-3921/13/9/1072

Internet

https://www.mdpi.com/2076-3921/13/9/1072

Similar Items