p110d PI3 kinase pathway: emerging roles in cancer
Class IA PI3Ks consists of three isoforms of the p110 catalytic subunit designated p110a, p110b and p110d which are encoded by three separate genes. Gain-of-function mutations on PIK3CA gene encoding for p110a isoform have been detected in a wide variety of human cancers whereas no somatic mutations...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2013-03-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00040/full |