Sclerostin and Osteocalcin: Candidate Bone-Produced Hormones

In addition to its structural role, the skeleton serves as an endocrine organ that controls mineral metabolism and energy homeostasis. Three major cell types in bone - osteoblasts, osteoclasts, and osteocytes – dynamically form and maintain bone and secrete factors with systemic activity. Osteocalci...

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Bibliographic Details
Main Authors: Jialiang S. Wang, Courtney M. Mazur, Marc N. Wein
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.584147/full