The Lipid-Modulating Effect of Tangeretin on the Inhibition of Angiopoietin-like 3 (ANGPTL3) Gene Expression through Regulation of LXRα Activation in Hepatic Cells

The Lipid-Modulating Effect of Tangeretin on the Inhibition of Angiopoietin-like 3 (ANGPTL3) Gene Expression through Regulation of LXRα Activation in Hepatic Cells

The excessive accumulation of TG-rich lipoproteins (TGRLs) in plasma is associated with dyslipidemia and atherosclerotic cardiovascular diseases (ASCVDs). Tangeretin is a bioactive pentamethoxyflavone mainly found in citrus peels, and it has been reported to protect against hyperlipidemia, diabetes,...

Full description

Bibliographic Details
Main Authors: Pei-Yi Chen, Tzu-Ya Chao, Hao-Jen Hsu, Chih-Yang Wang, Ching-Yen Lin, Wan-Yun Gao, Ming-Jiuan Wu, Jui-Hung Yen
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
TG-rich lipoproteins
tangeretin
lipoprotein lipase
ANGPTL3
LXRα
Online Access:https://www.mdpi.com/1422-0067/22/18/9853

Internet

https://www.mdpi.com/1422-0067/22/18/9853

Similar Items