A genetic variant in IL-6 lowering its expression is protective for critical patients with COVID-19

Abstract Critical coronavirus disease 2019 (COVID-19) is associated with high mortality and potential genetic factors have been reported to be involved in the development of critical COVID-19. We performed a genome-wide association study to identify the genetic factors responsible for developing cri...

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Bibliographic Details
Main Authors: Bo Gong, Lulin Huang, Yongquan He, Wen Xie, Yi Yin, Yi Shi, Jialing Xiao, Ling Zhong, Yi Zhang, Zhilin Jiang, Fang Hao, Yu Zhou, Huan Li, Li Jiang, Xingxiang Yang, Xiangrong Song, Yan Kang, Lin Tuo, Yi Huang, Ping Shuai, Yuping Liu, Fang Zheng, Zhenglin Yang
Format: Article
Language:English
Published: Nature Publishing Group 2022-04-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-022-00923-1