Incorporation of Perillyl Alcohol into Lipid-Based Nanocarriers Enhances the Antiproliferative Activity in Malignant Glioma Cells

Incorporation of Perillyl Alcohol into Lipid-Based Nanocarriers Enhances the Antiproliferative Activity in Malignant Glioma Cells

Perillyl alcohol (PA), a naturally existing monocyclic terpene related to limonene, is characterized by its poor aqueous solubility and very limited bioavailability. Its potential anti-cancer activity against malignant glioma has been reported. The aim was to develop PA-loaded lipid-based nanocarrie...

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Bibliographic Details
Main Authors: Tarek A. Ahmed, Alshaimaa M. Almehmady, Waleed S. Alharbi, Abdullah A. Alshehri, Fahad A. Almughem, Reem M. Altamimi, Manal A. Alshabibi, Abdelsattar M. Omar, Khalid M. El-Say
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Biomedicines
Subjects:
perillyl alcohol
lipid-based nanoformulations
docking
brain cancer
human farnesyltransferase
cell viability
Online Access:https://www.mdpi.com/2227-9059/11/10/2771

Internet

https://www.mdpi.com/2227-9059/11/10/2771

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