New fluorobenzamidine exerts antitumor activity against breast cancer in mice via pro-apoptotic activity

New fluorobenzamidine exerts antitumor activity against breast cancer in mice via pro-apoptotic activity

Abstract Background Breast cancer is one of the leading causes of cancer-related morbidities. The present study aimed to evaluate the efficacy of bithiophene-fluorobenzamidine (BFB) against breast cancer induced by 7,12-dimethylbenz(a)anthracene (DMBA) in female Swiss mice and reveal the underlining...

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Bibliographic Details
Main Authors: AbdelRahman B. Saleh, Nagwa H. Hassan, Mohamed A. Ismail, Wael M. El-Sayed
Format: Article
Language:English
Published: Springer 2022-09-01
Series:Discover Oncology
Subjects:
Bithiophene
Tamoxifen
Apoptosis
CDK1
ESR
Online Access:https://doi.org/10.1007/s12672-022-00554-6

Internet

https://doi.org/10.1007/s12672-022-00554-6

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