Identification of potential modulators of IFITM3 by in-silico modeling and virtual screening

Abstract IFITM3 is a transmembrane protein that confers innate immunity. It has been established to restrict entry of multiple viruses. Overexpression of IFITM3 has been shown to be associated with multiple cancers, implying IFITM3 to be good therapeutic target. The regulation of IFITM3 activity is...

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Bibliographic Details
Main Authors: Vikas Tiwari, Shruthi Viswanath
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-20259-8