Ochratoxin A induces abnormal tryptophan metabolism in the intestine and liver to activate AMPK signaling pathway

Ochratoxin A induces abnormal tryptophan metabolism in the intestine and liver to activate AMPK signaling pathway

Abstract Background Ochratoxin A (OTA) is a mycotoxin widely present in raw food and feed materials and is mainly produced by Aspergillus ochraceus and Penicillium verrucosum. Our previous study showed that OTA principally induces liver inflammation by causing intestinal flora disorder, especially B...

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Bibliographic Details
Main Authors: Weiqing Ma, Yang Fu, Shanshan Zhu, Daiyang Xia, Shuangshuang Zhai, Deqin Xiao, Yongwen Zhu, Michel Dione, Lukuyu Ben, Lin Yang, Wence Wang
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Animal Science and Biotechnology
Subjects:
AMPK
Metabolomics
Ochratoxin A
Tryptophan metabolism
Online Access:https://doi.org/10.1186/s40104-023-00912-6

Internet

https://doi.org/10.1186/s40104-023-00912-6

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