Lifespan extension induced by caffeine in Caenorhabditis elegans is partially dependent on adenosine signaling

Caffeine is a widely used psychoactive substance. Studies have shown that caffeine may play a protective role in aging-associated disorders. However, the mechanisms by which caffeine modulates aging are not yet clear. In this study, we have shown that caffeine increases Caenorhabditis elegans lifesp...

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Bibliographic Details
Main Authors: Jessika Cristina Bridi, Alexandre Guimarães de Almeida Barros, Letícia Reis Sampaio, Júlia Castro Damásio Ferreira, Félix Alexandre Antunes Soares, Marco Aurélio eRomano-Silva
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2015.00220/full