The combination of paeonol, diosmetin-7-O-β-D-glucopyranoside, and 5-hydroxymethylfurfural from Trichosanthis pericarpium alleviates arachidonic acid-induced thrombosis in a zebrafish model

The combination of paeonol, diosmetin-7-O-β-D-glucopyranoside, and 5-hydroxymethylfurfural from Trichosanthis pericarpium alleviates arachidonic acid-induced thrombosis in a zebrafish model

Trichosanthis fruit (TF) is a classic medicinal material obtained from Shandong, China. The peel of this fruit (Trichosanthis pericarpium, TP) is known to exert anti-thrombotic effects. However, the anti-thrombotic active components and mechanisms of TP have yet to be fully elucidated. Combined with...

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Bibliographic Details
Main Authors: Shenghua Lin, Honglin Ma, Shanshan Zhang, Wei Fan, Chuanlin Shen, Jiayu Chen, Meng Jin, Kun Li, Qiuxia He
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Pharmacology
Subjects:
Trichosanthis pericarpium
thrombosis
arachidonic acid
zebrafish
coagulation cascade
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1332468/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2024.1332468/full

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