The Role and Regulation of the NKG2D/NKG2D Ligand System in Cancer
The family of human NKG2D ligands (NKG2DL) consists of eight stress-induced molecules. Over 80% of human cancers express these ligands on the surface of tumour cells and/or associated stromal elements. In mice, NKG2D deficiency increases susceptibility to some types of cancer, implicating this syste...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-08-01
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Series: | Biology |
Subjects: | |
Online Access: | https://www.mdpi.com/2079-7737/12/8/1079 |