Living myocardial slices for the study of nucleic acid-based therapies

Gene therapy based on viral vectors offers great potential for the study and the treatment of cardiac diseases. Here we explore the use of Living Myocardial Slices (LMS) as a platform for nucleic acid-based therapies. Rat LMS and Adeno-Associated viruses (AAV) were used to optimise and analyse gene...

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Bibliographic Details
Main Authors: R. Nunez-Toldra, A. Del Canizo, I. Secco, L. Nicastro, M. Giacca, C. M. Terracciano
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1275945/full