Pathological significance of heme oxygenase-1 as a potential tumor promoter in heme-induced colorectal carcinogenesis
The significance of the heme-metabolizing enzyme heme oxygenase-1 (HMOX1) in the pathogenesis of colorectal cancer (CRC) has not been fully explored. HMOX1 cytoprotection is imperative to limit oxidative stress. However, its roles in preventing carcinogenesis in response to high levels of heme are n...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-04-01
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Series: | Cancer Pathogenesis and Therapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2949713223000216 |