Single Molecular Resolution to Monitor DNA Replication Fork Dynamics upon Stress by DNA Fiber Assay

DNA replication always encounters numerous endogenous and exogenous stresses during the cell cycle. Measuring the cell responses to stress has primarily relied on cell survival and incorporation of radioactive dNTPs, which is limited in resolution. A higher resolution is required to monitor how repl...

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Bibliographic Details
Main Author: Wenpeng Liu
Format: Article
Language:English
Published: Bio-protocol LLC 2021-12-01
Series:Bio-Protocol
Online Access:https://bio-protocol.org/en/bpdetail?id=4269&type=0