Packaging contests between viral RNA molecules and kinetic selectivity.

The paper presents a statistical-mechanics model for the kinetic selection of viral RNA molecules by packaging signals during the nucleation stage of the assembly of small RNA viruses. The effects of the RNA secondary structure and folding geometry of the packaging signals on the assembly activation...

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Bibliographic Details
Main Authors: Inbal Mizrahi, Robijn Bruinsma, Joseph Rudnick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-04-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1009913