Efficacy of Dolutegravir versus Darunavir in Antiretroviral First-Line Regimens According to Resistance Mutations and Viral Subtype

Efficacy of Dolutegravir versus Darunavir in Antiretroviral First-Line Regimens According to Resistance Mutations and Viral Subtype

Background: Dolutegravir (DTG)-based first-line regimens have shown superior efficacy versus darunavir (DRV)-based ones in randomized trials. We compared these two strategies in clinical practice, particularly considering the role of pre-treatment drug resistance mutations (DRMs) and of the HIV-1 su...

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Bibliographic Details
Main Authors: Pierluigi Francesco Salvo, Damiano Farinacci, Arturo Ciccullo, Vanni Borghi, Stefano Rusconi, Annalisa Saracino, William Gennari, Bianca Bruzzone, Ilaria Vicenti, Annapaola Callegaro, Antonio Di Biagio, Maurizio Zazzi, Simona Di Giambenedetto, Alberto Borghetti
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Viruses
Subjects:
HIV drug resistance
HIV genotypic resistance testing
HIV viral subtype
antiretroviral therapy
Online Access:https://www.mdpi.com/1999-4915/15/3/762

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https://www.mdpi.com/1999-4915/15/3/762

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