Streptococcus pneumoniae promotes lung cancer development and progression

Summary: Streptococcus pneumoniae (SP) is associated with lung cancer, yet its role in the tumorigenesis remains uncertain. Herein we find that SP attaches to lung cancer cells via binding pneumococcal surface protein C (PspC) to platelet-activating factor receptor (PAFR). Interaction between PspC a...

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Bibliographic Details
Main Authors: Ning Li, Huifen Zhou, Van K. Holden, Janaki Deepak, Pushpa Dhilipkannah, Nevins W. Todd, Sanford A. Stass, Feng Jiang
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222021964