Exploring personalized treatment for cardiac graft rejection based on a four-archetype analysis model and bioinformatics analysis

Exploring personalized treatment for cardiac graft rejection based on a four-archetype analysis model and bioinformatics analysis

Abstract Heart transplantation is the gold standard for treating patients with advanced heart failure. Although improvements in immunosuppressive therapies have significantly reduced the frequency of cardiac graft rejection, the incidences of T cell-mediated rejection (TCMR) and antibody-mediated re...

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Bibliographic Details
Main Authors: Hongjie Shi, Ming Yuan, Jie Cai, Jiajun Shi, Yang Li, Qiaofeng Qian, Zhe Dong, Gaofeng Pan, Shaoping Zhu, Wei Wang, Jianliang Zhou, Xianwu Zhou, Jinping Liu
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
Cardiac graft rejection
Co-expression network
Machine learning
Immune cell infiltration
Tyrosine kinase inhibitors
Endomyocardial biopsies
Online Access:https://doi.org/10.1038/s41598-024-57097-9

Internet

https://doi.org/10.1038/s41598-024-57097-9

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