A shear-thinning, ROS-scavenging hydrogel combined with dental pulp stem cells promotes spinal cord repair by inhibiting ferroptosis

A shear-thinning, ROS-scavenging hydrogel combined with dental pulp stem cells promotes spinal cord repair by inhibiting ferroptosis

Spinal cord injury (SCI) is a serious clinical disease. Due to the deformability and fragility of the spinal cord, overly rigid hydrogels cannot be used to treat SCI. Hence, we used TPA and Laponite to develop a hydrogel with shear-thinning ability. This hydrogel exhibits good deformation, allowing...

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Bibliographic Details
Main Authors: Yibo Ying, Zhiyang Huang, Yurong Tu, Qiuji Wu, Zhaoyu Li, Yifan Zhang, Huilei Yu, Annian Zeng, Hanzhi Huang, Jiahui Ye, Weiyang Ying, Min Chen, Zhiyi Feng, Ziyue Xiang, Qingsong Ye, Sipin Zhu, Zhouguang Wang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-04-01
Series:Bioactive Materials
Subjects:
Shear-thinning hydrogel
Dental pulp stem cells
Ferroptosis
ROS-Scavenging
Synaptic regulation
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X22004157

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http://www.sciencedirect.com/science/article/pii/S2452199X22004157

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