Comparing rates of mycobacterial clearance in sputum smear-negative and smear-positive adults living with HIV

Comparing rates of mycobacterial clearance in sputum smear-negative and smear-positive adults living with HIV

Abstract Background Pulmonary tuberculosis (TB) in people living with HIV (PLH) frequently presents as sputum smear-negative. However, clinical trials of TB in adults often use smear-positive individuals to ensure measurable bacterial responses following initiation of treatment, thereby excluding HI...

Full description

Bibliographic Details
Main Authors: Edith E. Machowski, Matebogo Letutu, Limakatso Lebina, Ziyaad Waja, Reginah Msandiwa, Minja Milovanovic, Bhavna G. Gordhan, Kennedy Otwombe, Sven O. Friedrich, Richard Chaisson, Andreas H. Diacon, Bavesh Kana, Neil Martinson
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Infectious Diseases
Subjects:
Tuberculosis
HIV
Smear microscopy
Xpert MTB/RIF
MGIT
Culturability
Online Access:https://doi.org/10.1186/s12879-021-06133-4

Internet

https://doi.org/10.1186/s12879-021-06133-4

Similar Items