Contribution of genetic ancestry and polygenic risk score in meeting vitamin B12 needs in healthy Brazilian children and adolescents

Contribution of genetic ancestry and polygenic risk score in meeting vitamin B12 needs in healthy Brazilian children and adolescents

Abstract Polymorphisms in genes related to the metabolism of vitamin B12 haven’t been examined in a Brazilian population. To (a) determine the correlation between the local genetic ancestry components and vitamin B12 levels using ninety B12-related genes; (b) determine associations between these gen...

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Bibliographic Details
Main Authors: Carlos Alessandro Fuzo, Fábio da Veiga Ued, Sofia Moco, Ornella Cominetti, Sylviane Métairon, Solenn Pruvost, Aline Charpagne, Jerome Carayol, Raul Torrieri, Wilson Araujo Silva, Patrick Descombes, Jim Kaput, Jacqueline Pontes Monteiro
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91530-7

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https://doi.org/10.1038/s41598-021-91530-7

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