Live-cell mapping of organelle-associated RNAs via proximity biotinylation combined with protein-RNA crosslinking
The spatial organization of RNA within cells is a crucial factor influencing a wide range of biological functions throughout all kingdoms of life. However, a general understanding of RNA localization has been hindered by a lack of simple, high-throughput methods for mapping the transcriptomes of sub...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2017-12-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/29224 |