Combinations of plasma cfDNA concentration, integrity and tumor markers are promising biomarkers for early diagnosis of non-small cell lung cancer

Combinations of plasma cfDNA concentration, integrity and tumor markers are promising biomarkers for early diagnosis of non-small cell lung cancer

Background: Circulating cell-free DNA (cfDNA) concentration and integrity as noninvasive biomarkers play an important role in cancer diagnosis, prognosis and therapy monitoring. However, few studies have been conducted on the combination of plasma cfDNA concentration, integrity and tumor markers (CE...

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Bibliographic Details
Main Authors: Sai Ren, Guichuan Zeng, Yuling Yi, Ling Liu, Hongmei Tu, Tingjia Chai, Liyi Hu
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Heliyon
Subjects:
Plasma cfDNA
DNA integrity
ALU repeated sequence
Quantitative real-time PCR
Non-small cell lung cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023080593

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http://www.sciencedirect.com/science/article/pii/S2405844023080593

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