Influenza A virus elicits peri-vascular adipose tissue inflammation and vascular dysfunction of the aorta in pregnant mice.

Influenza A virus elicits peri-vascular adipose tissue inflammation and vascular dysfunction of the aorta in pregnant mice.

Influenza A virus (IAV) infection during pregnancy initiates significant aortic endothelial and vascular smooth muscle dysfunction, with inflammation and T cell activation, but the details of the mechanism are yet to be clearly defined. Here we demonstrate that IAV disseminates preferentially into t...

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Bibliographic Details
Main Authors: Osezua Oseghale, Stella Liong, Madison Coward-Smith, Eunice E To, Jonathan R Erlich, Raymond Luong, Felicia Liong, Mark Miles, Shaghayegh Norouzi, Cara Martin, Sharon O'Toole, Robert D Brooks, Steven Bozinovski, Ross Vlahos, John J O'Leary, Doug A Brooks, Stavros Selemidis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010703

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https://doi.org/10.1371/journal.ppat.1010703

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