A systematic review of simulation studies which compare existing statistical methods to account for non-compliance in randomised controlled trials
Abstract Introduction Non-compliance is a common challenge for researchers and may reduce the power of an intention-to-treat analysis. Whilst a per protocol approach attempts to deal with this issue, it can result in biased estimates. Several methods to resolve this issue have been identified in pre...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-12-01
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Series: | BMC Medical Research Methodology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12874-023-02126-w |