Impact of Immunopathy and Coagulopathy on Multi-Organ Failure and Mortality in a Lethal Porcine Model of Controlled and Uncontrolled Hemorrhage

Impact of Immunopathy and Coagulopathy on Multi-Organ Failure and Mortality in a Lethal Porcine Model of Controlled and Uncontrolled Hemorrhage

Uncontrolled hemorrhage is a major preventable cause of death in patients with trauma. However, the majority of large animal models of hemorrhage have utilized controlled hemorrhage rather than uncontrolled hemorrhage to investigate the impact of immunopathy and coagulopathy on multi-organ failure (...

Full description

Bibliographic Details
Main Authors: Milomir O. Simovic, James Bynum, Bin Liu, Jurandir J. Dalle Lucca, Yansong Li
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
uncontrolled hemorrhagic shock
immunopathy
coagulopathy
MOF
mortality
swine
Online Access:https://www.mdpi.com/1422-0067/25/5/2500

Internet

https://www.mdpi.com/1422-0067/25/5/2500

Similar Items